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Nogle undersøgelser af mbrp og andre relevante mindfulness-interventioner

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Substance Abuse, 30:295–305, 2009
Copyright _cTaylor& Francis Group, LLC
ISSN: 08897077 print / 15470164 online
DOI: 10.1080/08897070903250084

Mindfulness-Based Relapse Prevention for Substance Use Disorders: A Pilot Efficacy Trial
Sarah Bowen, PhD, Neharika Chawla, MS, Susan E. Collins, PhD, Katie Witkiewitz, PhD, Sharon Hsu, BA, Joel Grow, BA, Seema Clifasefi, PhD, Michelle Garner, PhD, Anne Douglass, BA, Mary E. Larimer, PhD, Alan Marlatt, PhD.

ABSTRACT. The current study is the first randomized-controlled trial evaluating the feasibility and initial efficacy of an 8-week outpatient Mindfulness-Based Relapse Prevention (MBRP) program as compared to treatment as usual (TAU). Participants were 168 adults with substance use disorders who had recently completed intensive inpatient or outpatient treatment. Assessments were administered pre-intervention, post-intervention, and 2 and 4 months post-intervention. Feasibility of MBRP was demonstrated by consistent homework compliance, attendance, and participant satisfaction. Initial efficacy was supported by significantly lower rates of substance use in those who received MBRP as compared to those in TAU over the 4-month post-intervention period. Additionally,MBRP participants demonstrated greater decreases in craving, and increases in acceptance and acting with awareness as compared to TAU. Results from this initial trial support the feasibility and initial efficacy of MBRP as an aftercare approach for individuals who have recently completed an intensive treatment for substance use disorders.

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Depression, Craving, and Substance Use Following a Randomized Trial of Mindfulness-Based Relapse Prevention
Katie Witkiewitz,WashingtonStateUniversityVancouverand Sarah Bowen,UniversityofWashington

Objective: A strong relation between negative affect and craving has been demonstrated in laboratory and clinical studies, with depressive symptomatology showing particularly strong links to craving and substance abuse relapse. Mindfulness-based relapse prevention (MBRP), shown to be efficacious for reduction of substance use, uses mindfulness-based practices to teach alternative responses to emotional discomfort and lessen the conditioned response of craving in the presence of depressive symptoms. The goal in the current study was to examine the relation between measures of depressive symptoms, craving, and substance use following MBRP. Method: Individuals with substance use disorders (N _ 168; mean age 40.45 years, SD _ 10.28; 36.3% female; 46.4% non-White) were recruited after intensive stabilization, then randomly assigned to either 8 weekly sessions of MBRP or a treatment-as-usual control group. Approximately 73% of the sample was retained at the final 4-month follow-up assessment. Results: Results confirmed a moderated-mediation effect, whereby craving mediated the relation between depressive symptoms (Beck Depression Inventory) and substance use (Timeline Follow-Back) among the treatment-as-usual group but not among MBRP participants. MBRP attenuated the relation between postintervention depressive symptoms and craving (Penn Alcohol Craving Scale) 2 months following the intervention (f 2 _ .21). This moderation effect predicted substance use 4 months following the intervention (f 2 _ .18). Conclusion: MBRP appears to influence cognitive and behavioral responses to depressive symptoms, partially explaining reductions in postintervention substance use among the MBRP group. Although results are preliminary, the current study provides evidence for the value of incorporating mindfulness practice into substance abuse treatment and identifies a potential mechanism of change following MBRP.

Andre undersøgelser ved University of Washington af forskellige aspekter af mindfulness i misbrugsbehandling kan ses på:

www.mindfulrp.com/Research.html